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Antimicrobial Susceptibility

Phenotypic Detection of β-Lactamase Resistance in Gram-Negative Bacilli: Testing and Interpretation Guide
To detect isolates with AmpC, K1, and KPC enzymes, as well as those with ESBLs, it is desirable to test all Enterobacteriaceae with a combination of antibiotics that will allow detection of resistant mechanisms. In Dr. Paul Schreckenberger's laboratory, he and Violeta Rekasius, MT(ASCP) have expanded the ESBL confirmatory disk test to include 12 antibiotic disks and have applied the test to all members of the Enterobacteriaceae that have a susceptibility pattern that is suspicious for the presence of an ESBL, AmpC, K1 or KPC type resistance gene. Through the application of this test they have been able to successfully detect antibiotic resistance in many species of Enterobacteriaceae that would have not been detected using their automated susceptibility testing system.

Sanford Guide to Antimicrobial Therapy
Drawn entirely from published medical literature, The Sanford Guide to Antimicrobial Therapy consistently delivers convenient, comprehensive recommendations for treatment and prevention of bacterial, fungal, viral, parasitic and mycobacterial infections, surgical prophylaxis, and ancillary information covering pharmacology, adverse effects, drug-drug interactions and dose adjustments, all supported by commentary and references.

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